Endocrine Abstracts

Introduction: Abnormalities of lipid metabolism and arterial hypertension occur with increased frequency in hypothyroidism and are associated with a higher risk of premature atherosclerotic vascular disease. Therefore, a vigorous lipid lowering treatment seems mandatory, including quickly restoration of thyroid function, to reduce vascular risk. We evaluate benefits on lipid profile after intravenous thyroxine treatment in severe hypothyroid patients at three and thirty days.<...

Introduction: Nivolumab is an anti-programmed cell death-1 monoclonal antibody approved for the treatment of metastatic malignant melanoma. Several endocrine disorders have been reported as immune-related adverse effects. However, nivolumab-induced hypophysitis has a lower incidence than ipililumab.Case report: A 69-years old man with metastatic melanoma started to receive nivolumab. Ten weeks after the first cycle of nivolumab he presented hyperthyroidi...

Introduction: Bilateral sampling of the inferior petrosal sinuses is an accurate test to diagnose Cushing’s disease and distinguish it with the ectopic ACTH syndrome. The aim of the study was to review the petrosal sinus samplings carried out during last 10 years in our hospital.Methods and material: The medical histories of patients admitted for suspected Cushing’s disease in the last 10 years (from 2005 till 2015) were reviewed. There were se...